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Pilocarpine ophthalmic preparations should only be given during pregnancy when benefit outweighs risk. To avoid extensive neuroradiological tests, instillation of 1% pilocarpine solution is recommended as an aid in the diagnosis of non-neurogenic dilation of the pupil. The manufacturer recommends caution when administering pilocarpine ophthalmic to nursing women. , antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide) may antagonize the effects of topically administered cholinergic agents such as acetylcholine, carbachol, demecarium, echothiophate, isoflurophate, physostigmine, and pilocarpine. Keep Pilocarpine Solution out of the reach of children and away from pets. However, no specific interactions with Pilocarpine Solution are known at this time.
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